Size, Shape, and Sequence-Dependent Immunogenicity of RNA Nanoparticles
نویسندگان
چکیده
منابع مشابه
Size, Shape, and Sequence-Dependent Immunogenicity of RNA Nanoparticles
RNA molecules have emerged as promising therapeutics. Like all other drugs, the safety profile and immune response are important criteria for drug evaluation. However, the literature on RNA immunogenicity has been controversial. Here, we used the approach of RNA nanotechnology to demonstrate that the immune response of RNA nanoparticles is size, shape, and sequence dependent. RNA triangle, squa...
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ژورنال
عنوان ژورنال: Molecular Therapy - Nucleic Acids
سال: 2017
ISSN: 2162-2531
DOI: 10.1016/j.omtn.2017.10.010